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In HILIC mode, the mobile phase consisted of water containing 25 mmol/L AmAc, 25 mmol/L NH 4 OH (A) and ACN (B) in both positive and negative ion modes

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The tumor malignancy of liver cancer is modulated by the balance between HIC1, a transcription factor controlling the expression of a set of ferroptosis-upregulated factors, and HNF4A, another transcription factor controlling the expression of a set of ferroptosis-downregulated factors [97]

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