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Though, recently it has been pointed out that the molecular pathways controlled by these two transcription factors not only are highly overlapping, with Nrf2 able to modulate genes involved in lipid metabolism and LXR involved in the promotion of glutathione transferase, but they are also mutually interconnected 38,39,40

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2021, 10.: 10.3390/antiox10010089 ↑ Saccà SC, Roszkowska AM, Izzotti A: Environmental light and endogenous antioxidants as the main determinants of non-cancer ocular diseases