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Additionally, astrocytes modulate synaptic transmission and regulate immune reactions, further contributing to their important role in neural function [16] by interacting with endothelial cells through their end feet projections that encircle the basolateral side of cerebral capillaries, astrocytes exhibit a profusion of slender projections that sheath cerebral vasculature and enwrap both individual and clustered synaptic junctions [17] Astrocytes are the predominant cell type found in the CNS and are known to participate in a variety of physiological and biochemical processes [18]

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This work was supported by the Lorenzo and Pamela Galli Medical Research Trust