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[DOI] [PubMed] [Google Scholar] 19.Bansod S, Chilvery S, Saifi MA, Das TJ, Tag H, Godugu C

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Due to an ineffective blood-nerve barrier in our peripheral nervous system, exposure to some chemotherapeutic agents causes mitochondrial swelling in peripheral nerves, which lead to the opening of mitochondrial permeability transition pore and cytochrome c release resulting in degeneration of primary afferent sensory fibers