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Massimiliano Mazzone, PhD, Laboratory of Tumor Inflammation and Angiogenesis, VIB-KU Leuven, Leuven, Belgium, says, βWe previously demonstrated that both pharmacological and genetic inhibition of GLUD1 β an enzyme that converts L-glutamate into Ξ±-ketoglutarate and vice versa β in macrophages (a type of immune cells) significantly enhanced muscle regeneration and functional recovery in models of acute injury, ischemia, and aging
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[DOI] [PubMed] [Google Scholar] 80.GarcΓa-RodrΓguez C.E., Mesa M.D., Olza J., Vlachava M., Kremmyda L.S., Diaper N.D., Noakes P.S., Miles E.A., RamΓrez-Tortosa M.C., Liaset B., et al